Here’s what you need to know about the COVID ‘rebound’ as Biden moves back into quarantine


“I care less about rebound than I care about preventing serious illness. And Pax did it.”

White House COVID-19 response coordinator Ashish Jha speaking at a press conference on July 25. Anna Moneymaker/Getty Images

Even President Joe Biden tested positive for COVID-19 again on Saturday after he was cleared to move out of isolation – known as a “rebound” case Goes – White House Coronavirus Response Coordinator Ashish Jha urges people not to distrust Pfizer product PaxLovid. may cause a rebound.

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Relapses have been reported in people taking Paxlovid, an antiviral treatment from Pfizer that has been proven to reduce the risk of hospitalization or death in high-risk adults by about 90%. When Biden first came down with COVID-19, he was given Paxlovid, despite being vaccinated and promoted for extra precaution.

Jha, currently on leave as dean of the Brown University School of Public Health, took to twitter Sunday evening to allay concerns, pointing out that even though some people who take Paxclovid are experiencing cases of relapse, it is still doing its job very well.

It is important to know that for contagion purposes, rebound COVID-19 can occur, but generally, it does not cause serious illness, he said.

The numbers are hard to know for sure, because most people, whether they take Paxlovid or not, don’t get tested again soon after recovering, as Biden did.

He said he estimates about 5% of people taking Paxlovid relapse, which is a small minority. And people who don’t take Paxlovid can also relapse.

“In the clinical trial, the placebo group had almost the same rebound as the paxclovid group,” Jha said.

Jeremy Faust, a Brigham and women’s doctor who writes the Inside Medicine newsletter, posted Saturday that his estimated number of people who have rebounded is about 15-35% of people who take medication,

Although he agreed with Jha that it is still good practice to take paxlovid to prevent serious illness, the resulting rebound of paxlovid from infection is problematic, they wrote.

“People who have a Paxlovid rebound may be falsely reassured that they are no longer contagious,” he said. “If they leave the isolation and later become infectious again and infect others, they may inadvertently spread the virus to people who are able to contract the infection.”

According to the CDC, this is a possibility that patients taking paxlovid should be aware of.

“If you get better and then you get worse again or if you decide to get tested and you have a test that is positive, especially after a negative test result, the recommendation is to have at least five And have to continue isolating and masking again for days. The chief medical officer of the CDC’s COVID-19 response, Dr. Laurie Hicks said, at least 10 more days, in usa today,

But Jha said on Twitter that people at high risk should still get PaxLovid, despite the potential for rebound — “because I care less about rebound than I care about preventing serious disease. And Pax did it.” “

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